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In addition, giving alone or in combination with chlorimipramine seems to benefit these patients. Evidence against this serotonin theory includes the fact that low levels of ( have recovered and in some patients with mania. It seems likely that low levels of serotonin or noradrenaline do not cause depression, but that more complicated mechanisms involving a change in balance between these monoamines are involved. Despite evidence for and against, there remains one major problem with the monoamine theory of depression. All antidepressants take weeks to have an effect, which is far longer than it takes to alter brain amines.


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Your doctor will adjust the dose to find the best dose for you. Get the lowest prices on generic medications. Alcohol or marijuana cannabis can make you more dizzy or drowsy. This medication is removed by the kidneys. Do not increase the dose unless directed by your doctor. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Many people using this medication do not have serious side effects. It may harm an unborn baby.

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Authored by Michael D. Evers, MD

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