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Pulse methylprednisolone therapy is the recommended therapy for moderate to severe and active ophthalmopathy, but high dose pulse methylprednisolone therapy is marred by the chances of fulminant hepatic failure and the high cost of iv decadron cost. Dexamethasone pulse therapy can be considered as an alternative to pulse methylprednisolone therapy. A prospective randomized control trial was carried out in 21 patients comparing pulse dexamethasone therapy versus pulse methyprednisolone therapy in Graves's ophthalmopathy. Furthermore, dexa had a better effect on reduction of exophthalmos. Pulse dexamethasone therapy versus pulse methylprednisolone therapy for treatment of Graves's ophthalmopathy.


Infant mortality and morbidity from preterm birth can be reduced through interventions delivered to the mother before or during pregnancy, and to the preterm iv decadron cost after birth. Ten trials compared dexamethasone with betamethasone and two trials compared different regimens of the same drug in women at high risk of giving birth between 23 and 35 weeks of gestation. In four of the trials, women may have received repeat doses of corticosteroid. For women with ruptured membranes, the mean interval between hospital admission and birth was identical 7.

The oral solution contains citric acid, disodium edetate, flavoring, glycerin, methylparaben, propylene glycol, propylparaben, sorbitol and water. Primary or secondary adrenocortical insufficiency hydrocortisone or cortisone is the drug of choice; may be used in conjunction with synthetic miner-alocorticoid analogs where applicable;in infancy mineralocorticoid supplementation is of particular importance, congenital adrenal hyperplasia, hypercal-cemia associated with cancer, and nonsuppurative thyroiditis. Acquired autoimmune hemolytic anemia, congenital erythroid hypoplastic anemia Diamond-Blackfan anemia, idiopathic thrombocytopenic purpura in adults, pure red cell aplasia, and selected cases of secondary thrombocytopenia. Diagnostic testing of adrenocortical hyperfunction, trichinosis with neurologic or myocardial involvement, tuberculous meningitis with subarachnoid block or impending block when used with appropriate antituberculous chemotherapy. Acute exacerbations of multiple sclerosis, cerebral edema associated with primary or metastatic brain tumor, craniotomy, or head injury.


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You may receive dexamethasone injection in a hospital or medical facility, or you may be given the medication to use at home. Be sure that you understand these directions, and ask your healthcare provider if you have any questions. Ask your healthcare provider what to do if you have any problems using dexamethasone injection. Your doctor may change your dose of dexamethasone injection during your treatment to be sure that you are always using the lowest dose that works for you.

Your doctor may also need to change your dose if you experience unusual stress on your body such as surgery, illness, or infection. Tell your doctor if your symptoms improve or get worse or if you get sick or have any changes in your health during your treatment. Dexamethasone injection is also sometimes used to treat nausea and vomiting from certain types of chemotherapy for cancer and to prevent organ transplant rejection.

Talk to your doctor about the risks of using this medication for your condition. Your doctor may also prescribe or recommend a calcium or potassium supplement. Dexamethasone injection may cause children to grow more slowly. Your child's doctor will watch your child's growth carefully while your child is using dexamethasone injection. Talk to your child's doctor about the risks of giving this medication to your child. People who use dexamethasone injection for a long time may develop glaucoma or cataracts.

Talk to your doctor about the risks of using dexamethasone injection and how often you should have your eyes examined during your treatment. Dexamethasone injection may increase your risk of developing osteoporosis. Talk to your doctor about the risks of using this medication. Drugs which inhibit CYP 3A4 e. Dexamethasone is a moderate inducer of CYP 3A4.

Co-adminstration with other drugs that are metabolized by CYP 3A4 e. In addition, ketoconazole alone can inhibit adrenal corticosteroid synthesis and may cause adrenal insufficiency during corticos-teroid withdrawal. Nonsteroidal Anti-Inflammatory Agents NSAIDS: Concomitant use of aspirin or other nonsteroidal antiinflammatory agents and corticosteroids increases the risk of gastrointestinal side effects.

Aspirin should be used cautiously in conjunction with corticosteroids in hypoprothrombinemia.


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Side effects of allopurinol include skin rash and stomach upset and in rare cases a severe allergic reaction. Probenecid and sulfinpyrazone lower the uric acid level zyprexa 35 mg blood by increasing the amount of uric acid passed in the urine. They do this by competing for the transport mechanism responsible for tubular reabsorption of uric acid in the kidney. Side effects of these two drugs include nausea, skin rash, stomach upset or headaches. A drawback to the use of probenecid or sulfinpyrazone is that because of increased excretion of other organic acids that use the same transport system, the urine becomes more acidic than normal.

The gland consists of the posterior pituitary and the anterior pituitary (adenohypophysis). The functions of the two are not related but both are controlled by the hypothalamus. The posterior pituitary gland secretes two hormones, antidiuretic hormone and oxytocin. They are both synthesized in the hypothalamus and reach the posterior pituitary via a neural connection. ADH is secreted in response to an increase in plasma sodium chloride concentration or a decrease in circulating blood volume.

Adverse effects of loperamide are constipation, abdominal cramps, drowsiness and dizziness. Miscellaneous drugs used as adjuncts to radiography are summarized Wounds may become infected and need topical antibacterial treatment. Silver sulfadiazine cellulitis requires systemic treatment with an oral antibiotic, for example flucloxacillin or erythromycin. Contrast agents are used to enhance radiological examination of the body. Although air and gas can be used to provide negative contrast, positive contrast agents are most commonly used.

Authored by Dr. Gary Bakst, MD

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