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Lidocaine is the most commonly used local anaesthetic.
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In accordance with coronavirus precautions, Ohio Northern University has closed buildings to the public and transitioned to remote i. See all facts and figures. Ohio Northern University faculty members Ross Kauffman and Keith Durkin have taken an interdisciplinary approach to the multifaceted. Ohio Northern offers students an opportunity to grow and develop as a person - both in and out of the classroom. ONU leads in student engagement — internships, research, jobs and grad school.
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Chemically, general anaesthetics are a diverse group of drugs; they are all small lipid soluble molecules, but their mechanism of action is unknown. However, there are two main theories to explain the mechanism of action of general anaesthetics. These are the lipid theory and the protein theory. As anaesthetic potency is closely related to lipid solubility rather than to chemical structure, the lipid theory proposes that general anaesthetics interact with the lipid bilayer of the cell membrane.
Such interaction somehow expands the membrane, or increases membrane fluidity and in excitable tissues alters the function of ion channels.
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