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The insoluble fibres of fibrin enmesh red blood cells and platelets, which forms the clot itself. See Figure The process of coagulation is also dependent on the presence of calcium ions.
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Skin infections may require up to six weeks treatment with a minimum of two to three weeks.
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In order to get to their site of action in the body, drugs have to be administered in some way. There are two major routes of drug administration: enteral and parenteral. Enteral means to do with the gastrointestinal tract and includes oral and rectal administration. The parenteral route includes all other means of drug administration.
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Examples of centrally acting antihypertensives are methyldopa and clonidine.
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Osteoporosis can be prevented or reduced by regular exercise and adequate dietary intake of calcium and vitamin D throughout life but especially in adolescence.
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Stomach acid and enzymes can destroy some drugs and they have to be protected by an enteric coat so they pass unharmed into the small intestine.
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