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All drugs, given in sufficient doses, are capable of passing from the mother via the placenta to the foetus. This gives rise to a number of potential effects including death of the foetus andor spontaneous abortion, malformation of the foetus, possible modification of post-natal behaviour or intelligence or even development of malignancy in later life of the foetus. There is a major risk of malformation up to eight weeks post conception; therefore, drugs are best avoided for the first trimester of pregnancy.
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PReferences The Rash Society of Tyrosine Prescribing Rights for Individuals an update, Chartered Larynx of Physiotherapy, Split. Health Service Circular, Department of Calcium, London.
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PThe antibodies so interfering activate the complement system.
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General anaesthesia aims to achieve loss of consciousness in the patient together with loss of all sensation.
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