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Atorvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. Atorvastatin and other statins including lovastatin, pravastatin, rosuvastatin, fluvastatin, and simvastatin are considered first-line treatment options for dyslipidemia. Atorvastatin was first synthesized in by Dr. Bruce Roth and approved by the FDA in Atorvastatin is indicated for the treatment of several types of dyslipidemias, including primary hyperlipidemia and mixed dyslipidemia in adults, hypertriglyceridemia, primary dysbetalipoproteinemia, homozygous familial hypercholesterolemia, and heterozygous familial hypercholesterolemia in adolescent patients with failed dietary modifications. Dyslipidemia describes an elevation of plasma cholesterol, triglycerides or both as well as to the presence of low levels of high-density lipoprotein.


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Common side effects include weight gain, movement disorders, dizziness, feeling tired, constipation, and dry mouth. Olanzapine was patented in and approved for medical use in the United States in In the final two steps, 5-methyl 2-nitrophenyl aminothiophenecarbonitrile was reduced with stannous chloride in ethanol to give the substituted thienobenzodiazepine ring system, and this was treated with methylpiperazine in a mixture of dimethyl sulfoxide and toluene as solvent to produce the drug. The first-line psychiatric treatment for schizophrenia is antipsychotic medication, with olanzapine being one such medication. The National Institute for Health and Care Excellence, the British Association for Psychopharmacology, and the World Federation of Societies for Biological Psychiatry suggest that little difference in effectiveness is seen between antipsychotics in prevention of relapse, and recommend that the specific choice of antipsychotic be chosen based on a person's preference and the drug's side-effect profile. Agency for Healthcare Research and Quality concludes that olanzapine is not different from haloperidol in the treatment of positive symptoms and general psychopathology, or in overall assessment, but that it is superior for the treatment of negative and depressive symptoms.

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In many patients, removal of the thymus gland can induce remission of the disease. Drug therapy includes the use of anticholinesterase drugs, anti-inflammatory corticosteroids and immunosuppressant drugs in resistant cases. The first two case studies are about hypothetical patients who might be seen in the podiatry clinic. However, other health care professionals might see similar patients for other reasons. The third case study is a patient who any health care professional might see for different reasons.

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