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It is possible to predict, and to some extent avoid, likely adverse effects in particular populations using knowledge of factors that affect the four processes above in different patient groups.
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Although the cause of most CNS disorders is unknown, alteration in the function of neurotransmitters or their receptors is implicated in many of them.
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The pancreas is a large organ containing exocrine and endocrine tissue.
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Drug interactions with sulfonylureas and biguanides are common: non-steroidal antiinflammatory drugs, warfarin, alcohol, monoamine oxidase inhibitors, some uricosurics, some antibacterials and some antifungals can interact with them.
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Inhibition of COX by NSAIDs reduces rather than abolishes inflammation because the drugs do not inhibit production of other mediators of inflammation.
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Since local anaesthetics are often used to prevent pain, they are also known as local analgesics.
Podiatric surgeons are not doctors (that is Registered Medical Practitioners). Podiatric surgeons have specialized throughout their training, purely in the treatment of one area of the body, the foot and ankle.
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Flucloxacillin is not affected by penicillinase and is used for staphylococcus infection. Resistance to penicillins also occurs by reduction in entry of the drug into the bacterial cell and by alteration of penicillin binding protein.
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It may be due to a deficit of noradrenaline andor dopamine in the prefrontal cerebral cortex. Treatment with stimulant drugs, for example dexamphetamine, seems to have a calming effect in some patients.
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Halofantrine can also cause cardiac arrhythmia and should be avoided in patients with arrhythmias. These drugs aim to eliminate the resting stage of the parasite in the liver.